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Aripiprazole and risperidone in the treatment of 120 patients with schizophrenia compared

ybetterthanRisperidone. Conclusion: Aripi · prazolethetreatmentisadvantageoustotheexaltationschizophreniadiseasesuffererlifequantity. 【Keywords】 Aripiprazole; Risperidone; Theschizophreniadisease to explore aripiprazole (trade name: Booz SD) for mental patients quality of life, our study of risperidone for the control, the report is as follows. 1 Department of objects and methods 1.1 objects from January 2005 to January 2008 patients in our hospital,asics tiger shoes, in line with the Chinese Classification and Diagnostic Criteria of Mental Disorders version 5 diagnostic criteria for mental disorder; first onset, duration ≤ 5 years; not taking any antipsychotics; positive and negative syndrome scale (PANSS) total score ≥ 6o minutes; aged 19 to 64 years; junior high school and above; exclude serious physical illness, previous history of allergies, alcohol and drug dependency, pregnancy and lactation persons; obtain informed consent. A total of 120 patients, randomly divided into two groups. Aripiprazole group, 60 cases, 40 cases of male and female 2O cases; aged 18 to 64 years, mean (25.24-7.5) years; duration of 1-55 months, mean (22 ± 12) months. Risperidone group 6o cases, 36 males and 24 females; aged 18-65 years, mean (25 ± 8) years; course of 1-55 months, mean (22 ± 13) months. PANSS score above two groups and there was no significant difference (P> 0.05). 1.2 Methods of aripiprazole initial dose of 5mg / d, the maximum dose of 25mg / d. The initial dose of risperidone lms / d, the maximum dose of 4mg / d. 8 weeks. Can be combined with benzodiazepine drugs. Not used for other antipsychotic drugs and electric shock treatment. Scale with the PANSS and side effects (TESS) respectively 2.4,mbt scarpe prezzi,6.8 week before treatment and 1 of the assessment. At the same time as blood pressure, pulse,scarpe nike 2011, body mass (weight), blood, urine, liver, kidney function, blood sugar,timberland scarpe, ECG and EEG and other tests. SPSS10.0 software for data input, or x t test. 2 Results 2.1 PANSS scores between the two groups after treatment, PANSS scores were significantly reduced compared with before treatment, the difference was statistically significant (P 0.05), show that the two groups is similar. Table 1. 2.2 GQOLI a 74 score in the two groups before treatment GQOLI a 74 total score and factor scores of each dimension there was no significant difference (P> 0.05). 8 weeks of treatment groups GQOLI a 74 total score, physical health dimension, the dimension of mental health, social function dimensions of each factor increased significantly compared with before treatment (P 0.05). 3, the spirit of the discussion quality of life assessment of patients as the extent of damage and an important indicator of intervention effect, increasingly concerned about domestic scholars and research. The results form Nick, aripiprazole and risperidone can significantly improve the quality of life of patients with mental disorders,new balance outlet, treatment of mental disorders have a significant effect, but aripiprazole than risperidone in addition to eating the body of the health maintenance functions degrees and the social function dimension scores were significantly better, indicating that the improvement of mental patients better quality of life, which may be due to aripiprazole mainly presynaptic dopamine (D:) A receptors and 5-HT (5 a HT1A ) receptors are part of the emotional effect.
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