ajf 5 Asherson's Syndrome A Brief Review o jordan

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The signs and symptoms are also noticeable in women at the time of pregnancy or in the weeks following delivery of a baby (puerperium) and may resemble [link widoczny dla zalogowanych]HELLP syndrome or be related to malignancies. Symptoms deviate from example to example depending upon the particular organ schemes affected. Asherson’s syndrome may quickly cause dangerous multiorgan inactivity.
Asherson’s syndrome is an intense form of antiphospholipid syndrome (APS), an autoimmune disease in which blood clots appear in respect to the presence of antiphospholipid antibodies in the person. Antibodies are differentiated protein substances developed by the patient's immune system to oppose infections.
It is not understood why persons with antiphospholipid syndrome occasionally have the predilection to be "slung" into an extreme or disastrous multiorgan disease, while similar inducers in other patients will only cause continual large vessel clotting (thrombosis).
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Asherson’s syndrome is also called Catastrophic Antiphospholipids Disease. Disorders like infections, immunizations, bruises created by physical injury and inactivity in the anticoagulation mechanics of the person almost always function as causative agents of Asherson's syndrome.
Phospholipids are available throughout the body system. The reason such antibodies strike protein substances, as well as the protocol by which they bring about blood clots, isn't completely understood.
Ronald Asherson and Catastrophic Antiphospholipids Syndrome
He described the clinical features of the disease [link widoczny dla zalogowanych], helped discover the symptomatic criteria, suggested the preferable treatment, and in time reported on its medical prognosis.
In autoimmune diseases, antibodies erroneously strike healthy tissues. In APS and Asherson’s syndrome, antibodies erroneously attack specific proteins that attach to phospholipids, that are fat particles that are associated with the normal activity of cell membranes.
Ronald Asherson passed away in May 2008. Raised in South Africa [link widoczny dla zalogowanych], he trained in medicine in Cape Town, South Africa and then performed one of his post-doctorates alongside Graham Hughes (“Hughes syndrome”) in England. His major claim to popularity is the verbal description of the catastrophic antiphospholipid syndrome (CAPS).
Signs and Symptoms of Asherson’s Syndrome
Asherson’s syndrome can appear in people with primary or secondary APS or in patients who have lupus or additional autoimmune diseases. In certain instances, no prior clinical history of these diseases may be there. The direct etiology (cause) of Asherson’s syndrome is still unidentified.
Miesbach, W. "Malignancies and Catastrophic Anti-phospholipid Syndrome." (2009. Clinical Reviews in Allergy and Immunology. 36; (2-3): 91-7. June.
Yehuda Shoenfeld, and Ricard Cervera. (2008). "Asherson’s Syndrome of the Catastrophic Antiphospholipid Antibodies." The Journal of Rheumatology. (35); 10: 2066-68. October 1.
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The syndrome is particularly frequent among individuals with antiphospholipid syndrome who go through a cessation of the anticoagulation mechanics associated with continual bleeding in the system. It is often observed in individuals who have previously experienced from a simple/classic episode of antiphospholipid syndrome.